Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review

Abstract

Moringa oleifera (M. oleifera) is an angiosperm plant, native of the Indian subcontinent, where its various parts have been utilized throughout history as food and medicine. It is now cultivated in all tropical and sub-tropical regions of the world. The nutritional, prophylactic, and therapeutic virtues of this plant are being extolled on the Internet. Dietary consumption of its part is therein promoted as a strategy of personal health preservation and self-medication in various diseases. The enthusiasm for the health benefits of M. oleifera is in dire contrast with the scarcity of strong experimental and clinical evidence supporting them. Fortunately, the chasm is slowly being filled. In this article, I review current scientific data on the corrective potential of M. oleifera leaves in chronic hyperglycemia and dyslipidemia, as symptoms of diabetes and cardiovascular disease (CVD) risk. Reported studies in experimental animals and humans, although limited in number and variable in design, seem concordant in their support for this potential. However, before M. oleifera leaf formulations can be recommended as medication in the prevention or treatment of diabetes and CVD, it is necessary that the scientific basis of their efficacy, the therapeutic modalities of their administration and their possible side effects be more rigorously determined.

Keywords: Moringa oleifera, cardiovascular disease, diabetes, phytotherapy, natural products
Post by Matorwmasen

My name is Clement Matorwmasen. Together with my wife I have co-founded Green Gold Social Enterprise. Since childhood I have always been a social and environmental activist and I was a youth leader in many activist groups. As a child I grew up in difficult circumstances when my parents abandoned me and I grew up at the homes of different foreign missionaries. As a teenager I re-established the contact with my family members and my tribe and I learned I was high up in the royal family lineage. I now have very strong ties to my tribe and I want to make a difference in not only their lives, but that of all Ghanaians. When I reconnected with my family, I was already running several not-for-profit projects trying to improve the living conditions in several poor communities, like organising finances for a community boreholes to improve access to clean drinking water. I was doing this alongside my teaching job as an IT-specialist at a tertiary institution. In 2007 my boss and mentor introduced me to Moringa. I was intrigued and went to learn more about the plant and all its qualities and I saw it as a potential solution to combat malnutrition in our communities. This inspired me to set up my own NGO called Drive Aid Ghana and we started promoting the usage and cultivation of Moringa. I was happy that I could make a difference for some people, but scaling and sustaining our activities were highly problematic. Initially I was able to interest farmers in growing Moringa, but mostly they ended up cutting it down because they were not able to generate income from it. This was because there was no established local market. They also challenged me: ‘if Moringa is so useful and if you can earn so much money with it, then why don’t you do it yourself?’ These experiences made me think and slowly the idea of starting a social enterprise to promote Moringa as a cash crop started to develop. With the full support of my wife I handed over my IT-business to my brother and went full-time into developing our social enterprise Green Gold. We have been donated an abandoned state farm of 3000 ha by one of our communities, which we are currently developing into a Moringa plantation and processing factory. My quest is simply to make a difference in other people’s lives and to make the world a better place one smile at a time, Moringa is my pivot point for sustainable development

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